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破伤风抗毒素注射后饮酒出现过敏性休克
引用本文:胡幼红. 破伤风抗毒素注射后饮酒出现过敏性休克[J]. 药物不良反应杂志, 2008, 10(1): 64-64
作者姓名:胡幼红
作者单位:郑州市第五人民医院药剂科,郑州450003
摘    要:1名19岁男性因外伤,在皮试阴性后肌内注射破伤风抗毒素1500IU。半小时后,患者饮酒约20ml,即出现头晕,全身皮肤出现风团,耳垂、口唇肿大、胸闷、心慌、出冷汗、面色苍白、呼吸困难等症状。查体P108次/min,R28次min,BP60/30mmHg。经吸氧、抗过敏、补充电解质等对症治疗后,症状逐渐缓解,生命体征恢复正常。

关 键 词:破伤风抗毒素    过敏性休克

Allergic shock after injection of tetanus antitoxin and drinking spirits in succession
Hu Youhong. Allergic shock after injection of tetanus antitoxin and drinking spirits in succession[J]. Adverse Drug Reactions Journal, 2008, 10(1): 64-64
Authors:Hu Youhong
Affiliation:Hu Youhong (Department of Pharmacy, Zhengzhou the Fifth People's Hospital, Zhengzhou 450003, China)
Abstract:A 19-year-old man with wound received IM tetanus antitoxin 1500 IU following a negative skin test. Half an hour later, he drank about 20 ml of spirit. He developed dizziness, generalized wheal, ear lobe and lip swelling, chest distress, palpitation, cold sweat, pallor, and dyspnoea immediately, Physical examination revealed a pulse rate of 108 beats/min, a respiratory rate of 28 breaths/min, and a BP of 60/30mmHg. After symptomatic treatment with oxygen, anti-anaphylaxis, and electrolyte supplements, the symptoms resolved gradually, and his vital signs returned to normal ranges.
Keywords:tetanus antitoxin  spirit  allergic shock
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