小剂量骨水泥经皮椎体成形术治疗老年人椎体压缩骨折的临床研究

目的探讨小剂量骨水泥经皮椎体成形术(PVP)在治疗骨质疏松性椎体压缩骨折中的疗效。方法2005年1月至2008年12月,应用小剂量骨水泥PVP治疗骨质疏松性椎体压缩骨折30例,并与同期进行常规PVP的30例患者疗效进行对比。结果60例患者术后获12～24个月(平均16.8个月)随访,小剂量骨水泥填充患者的骨水泥渗漏率平均为13.8%,常规填充的患者骨水泥渗漏率平均为29.9%,两组差异有统计学意义(P<0.05)。术后第3天两组之间的疼痛缓解程度差异无统计学意义(P>0.05)。两组病例手术后第3天拍摄胸腰椎X线与术前X线相比,椎体前、中、后缘高度及椎体后凸角Cobb角在手术前后差异均有统计学意义(P<0.05)。结论PVP治疗骨质疏松性椎体压缩骨折效果满意,小剂量骨水泥充填并不影响疗效,而且可以预防骨水泥渗漏。

Clinical Study on the Elderly Vertebral Compression Fractures Treated by Percutaneous Vertebroplasty

Objective To evaluate the effects of percutaneous vertebroplasty of low-dose bone cement injection in treating for osteoporotic vertebral compression fractures. Methods From January 2005 to December 2008,30 cases of osteoporotic vertebral compression fractures were treated by PVP of low-dose bone cement. The efficacy was compared with 30 patients who were treated by conventional PVP in the same period. Results All the cases were followed up 12 to 24 months with an average of 16.8 months. Bone cement leakage rate of patients who were filled with low-dose bone cement was 13.8% and the rate of conventional treatment was 29.9%,there were statistically significant differences (P <0.05). After 3 days between the two groups easement of pain had no statistically significant difference (P >0.05). All cases were taken X-ray,vertebral height and Cobb angle had statistically significant differences (P <0.05) before and after surgery. Conclusion The curative effect of PVP was good in treating osteoporotic vertebral fractures. Small doses of bone cement filled does not affect the efficacy and can prevent leakage of bone cement.