Two patients with acute hepatitis B with suspected sexual transmission of hepatitis G virus |
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Authors: | Eiji Tanaka Yoshiyuki Nakatsuji Masakazu Kobayashi Koji Orii Kendo Kiyosawa |
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Institution: | (1) Second Department of Internal Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390, Japan, JP |
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Abstract: | Two patients with acute hepatitis B with suggested sexual transmission of hepatitis G virus (HGV) are reported. A total of
18 patients with community acquired acute hepatitis B were analyzed in this study. Two of the 18 patients (patients 1 and
2) were positive for serum HGV RNA at the initial consultation. Both patients had had sexual contact with prostitutes several
weeks before the onset of acute hepatitis, and hepatitis B virus (HBV) was suggested to be infected through the sexual contacts.
These patients showed no other history of exposure to possible transmission routes for blood-borne hepatitis viruses. Patient
1 was diagnosed as with acute HGV infection because the antibody to HGV envelope-2 protein seroconverted to positive during
the course of acute hepatitis. HGV RNA was negative in a serum sample collected from patient 2 before the onset of acute hepatitis,
also suggesting acute HGV infection. These results indicate that in patients 1 and 2 HGV was infected along with HBV through
sexual contact. The clinical manifestations of acute hepatitis in the two patients with HGV co-infection did not differ from
those in the 16 patients with HBV infection alone.
(Received Aug. 6, 1997; accepted Oct. 30, 1997) |
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Keywords: | : hepatitis G virus transmission route sexual contact acute hepatitis B |
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