凝血功能检测在临产孕妇中的临床意义

目的探讨临产孕妇凝血功能指标监测的临床意义。方法采用日本SysmexCA-1500全自动凝血分析仪，对181例临产孕妇和83例非孕健康妇女进行了凝血酶原时间（PT）、活化部分凝血活酶时间（APTT）、凝血酶时间（TT）及纤维蛋白原（Fib）指标检测和分析。结果临产孕妇的Fib明显高于健康对照组，两组差异有统计学意义（P〈0．01）；APTT与健康对照组比较，差异无统计学意义（P〉0．05）；PT及TT明显低于健康对照组，差异有统计学意义（P〈0．01）。结论临产孕妇血液处于高凝状态，临产前进行凝血功能指标检测，对预防临产孕妇在分娩过程中及产后可能出现的大出血以及预防弥漫性血管内凝血的发生和诊断有着重要意义。

Clinical significance of blood coagulation function detection in parturient women

Objective To evaluate the clinical signification of blood coagulation function indices in parturient women. Methods Sysmex CA-1500 was applied to measuring plasma prothrombin time （PT）, activated partial thromboplastin time（APTT） ,thrombin time（TT） and fibrinogen（Fib） in 181 cases of parturient women（parturient women group） and 83 cases of non-pregnant healthywomen（control group） ,and then the results were compared and analyzed. Results Compared with that of control group, the level of Fib in parturient women group was significantly higher,but PT and TT markedly lower（P〈0.01 ）. There wasn＇t statistical difference in level of APTT between parturient women group and control group（P〉0.05）. Conclusion As the blood of parturient women is in hypercoagulable state, the detection of coagulation indices is important to prevent hemorrhoea during and after parturition as well as DIC.