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人工肝支持系统治疗重型肝炎临床疗效评价
引用本文:周曙岚,吴艾萌,朱孝武,杨静. 人工肝支持系统治疗重型肝炎临床疗效评价[J]. 中国临床药理学与治疗学, 2002, 7(6): 552-554
作者姓名:周曙岚  吴艾萌  朱孝武  杨静
作者单位:合肥市传染病医院一病区,合肥,230022
摘    要:目的 :评估人工肝支持系统 (ALSS)治疗重型肝炎的临床疗效。方法 :治疗组 32例和对照组 38例 ,两组均按重型肝炎常规综合治疗 ,治疗组同时给予ALSS治疗。结果 :ALSS治疗后 ,重型肝炎患者症状明显改善 ,肝功能等明显好转。治疗组好转率4 6 .9% ,对照组为 2 3.2 % ;两组差异有显著性 (P <0 .0 5 )。重型肝炎早、中、晚期应用ALSS治疗 ,好转率分别为 80 .0 %、5 0 .0 %和 10 %。结论 :ALSS治疗重型肝炎疗效肯定 ,宜在早、中期进行

关 键 词:人工肝支持系统 重型肝炎 评价研究
文章编号:1009-2501(2002)06-0552-03
修稿时间:2002-07-22

Evaluation of the effect of artificial liver support system on severe hepatitis
ZHOU Shu Lan,WU Ai Meng,ZHU Xiao Wu,YANG Jing First Ward,Infection Hospital of Hefei,Hefei. Evaluation of the effect of artificial liver support system on severe hepatitis[J]. Chinese Journal of Clinical Pharmacology and Therapeutics, 2002, 7(6): 552-554
Authors:ZHOU Shu Lan  WU Ai Meng  ZHU Xiao Wu  YANG Jing First Ward  Infection Hospital of Hefei  Hefei
Affiliation:ZHOU Shu Lan,WU Ai Meng,ZHU Xiao Wu,YANG Jing First Ward,Infection Hospital of Hefei,Hefei 230022
Abstract:AIM: To evaluate the therapeutic effect of artificial liver support system (ALSS) in the treatment of severe hepatitis. METHODS: Seventy patients with severe hepatitis were enrolled in two groups: treatment group (n=32) given ALSS combined with a routine treatment, and control group (n=38) only given the routine treatment. RESULTS: The liver functions of patients in treatment group were significantly improved after ALSS therapy. The total clinical efficacy rates in treatment group and control group were 46.9 % and 23.2 %, respectively (P< 0.05 ). The efficacy rates of patients receiving ALSS therapy in early, middle and late stage were 80.0 %, 50.0 % and 10.0% respectively. CONCLUSION: ALSS is effective in treatment of severe hepatitis, especially in early and middle stage.
Keywords:artificial liver support system  severe hepatitis  evaluation study
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