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Effectiveness of haemophilus influenzae type B conjugate vaccine for prevention of meningitis in Senegal |
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| Authors: | Fleming Jessica A Dieye Yakou Ba Ousseynou Mutombo wa Mutombo Boniface Diallo Ndiouga Faye Pape Coumba Ba Mamadou Cisse Moussa Fafa Diallo Aissatou Gaye Ba Mady Slack Mary P E Weiss Noel S |
| Institution: | Vaccine Access and Delivery, PATH, Seattle, WA, USA. jfleming@path.org |
| Abstract: | A total of 24 cases of hospitalized, laboratory-confirmed Haemophilus influenzae type b (Hib) meningitis were identified through a regional pediatric bacterial meningitis surveillance system. Each case was matched by age and residence to 4 neighborhood controls. The adjusted vaccine effectiveness for ≥ 2 doses was 95.8% (95% confidence interval, 67.9%-99.4%). Hib vaccine appears to be highly effective in preventing Hib meningitis in Senegal. |
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