Abstract: | We compared the clinical characteristics and survival rate of 52 patients of unilateral breast cancer with family history (UFH) with 665 patients with no family history (UNFH). The distribution of clinical stage and histologic type were almost equal between two groups. The estrogen receptor-positive rate was significantly higher in UFH than UNFH. As for a disease-free survival, there was no difference, however, the overall survival seemed to be better in UFH than in UNFH. These results suggest that the survival of the UFH may depend on a higher incidence of estrogen receptor-positive cases because UFH responds well to hormonal treatment after relapse. |