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EFFECTS OF TWO DIFFERING HALOTHANE CONCENTRATIONS ON THE METABOLIC AND ENDOCRINE RESPONSES TO SURGERY |
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| Authors: | LACOUMENTA, S. PATERSON, J. L. BURRIN, J. CAUSON, R. C. BROWN, M. J. HALL, G. M. |
| Affiliation: | Hammersmith Hospital Royal Post-graduate Medical School London W12 0HS. Department of Anaesthetics Hammersmith Hospital Royal Post-graduate Medical School London W12 0HS. Department of Medicine Hammersmith Hospital Royal Post-graduate Medical School London W12 0HS. Department of Clinical Pharmacology Hammersmith Hospital Royal Post-graduate Medical School London W12 0HS. |
| Abstract: | The effects of two differing concentrations of halothane, 2.1MAC or 1.2 MAC, on the metabolic and endocrine responses toabdominal hysterectomy were investigated. The changes in bloodglucose and lactate values, and plasma glycerol, cortisol, insulinand catecholamine concentrations were similar in both groups.We conclude that high concentrations of halothane do not suppressthe responses to pelvic surgery, and that accurate quantificationof the dose of halothane, within the concentration range of1.2 to 2.1 MAC, is not essential in studies of metabolic changesassociated with surgery. |
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