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椎间盘退变模型的研究进展
引用本文:史新瑞,徐海栋,刘晓伟.椎间盘退变模型的研究进展[J].国际病理科学与临床杂志,2017,37(2).
作者姓名:史新瑞  徐海栋  刘晓伟
作者单位:南京军区总医院骨科,南京,210002
基金项目:国家青年自然科学基金(81501925).This work was supported by National Natural Science Foundation of Youth,P.R.China
摘    要:椎间盘退变疾病发病率越来越高,但退变的机制尚不明确.椎间盘退变模型是现今研究椎间盘退变疾病的主要方式,退变模型主要分为体内退变模型和体外退变模型两大类.两种退变模型从不同角度研究椎间盘退变的病理生理过程,为揭示退变机制及预防、治疗椎间盘退变疾病起着重要作用.本文就目前国内外关于两种不同椎间盘退变模型研究的进展作一综述.

关 键 词:椎间盘退变  退变模型  进展

Research progress on the intervertebral disc degeneration model
SHI Xinrui,XU Haidong,LIU Xiaowei.Research progress on the intervertebral disc degeneration model[J].Journal of International Pathology and Clinical Medicine,2017,37(2).
Authors:SHI Xinrui  XU Haidong  LIU Xiaowei
Abstract:The incidence of intervertebral disc degeneration disease is growing higher,but the degeneration of the mechanism is still unclear.Intervertebral disc degeneration model is the main way to study intervertebral disc degeneration disease at present.The disc degeneration model is mainly divided into two types:in vivo model and in vitro model.Two kinds of degeneration models study the pathophysiological process ofintervertebral disc degeneration in different angles.The models play an important role in revealing the degeneration mechanism,preventing and treating intervertebral disc degeneration.This review tries to summarize the status and progress of disc degeneration models in China and abroad.
Keywords:disc degeneration  degenerate models  progress
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