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小血管硬化剂治疗应用进展
引用本文:乐张慧,张倩,王焱,方方. 小血管硬化剂治疗应用进展[J]. 国际皮肤性病学杂志, 2017, 43(5). DOI: 10.3760/cma.j.issn.1673-4173.2017.05.004
作者姓名:乐张慧  张倩  王焱  方方
作者单位:中国医学科学院 北京协和医学院 皮肤病医院皮肤外科 江苏省皮肤病与性病分子生物学重点实验室, 南京,210042
基金项目:北京协和医学院协和青年基金,PUMC Youth Fund
摘    要:硬化剂疗法是一种治疗血管扩张的有效手段,其通过注射硬化剂使血管成为纤维条索,最终被周围组织吸收,以达到治疗血管异常曲张或美容的目的.硬化剂疗法是治疗皮内小静脉曲张,包括网状静脉曲张和毛细血管扩张的首选疗法,对低流量血管畸形的治疗也有较好疗效.硬化剂的种类、泡沫硬化剂的稳定性、注射方法等因素均会影响临床应用的效果.随着硬化剂在临床的广泛应用,硬化剂泡沫制作的不断改进,对部分硬化剂的使用浓度与剂量已达成了共识,一些关于硬化疗法的研究和影像等新兴技术的应用也使硬化剂疗法取得进展,使得对硬化疗法的有效性及安全性有了更深入的认识.

关 键 词:血管  毛细血管扩张  血管畸形  硬化疗法  治疗应用

Application of sclerotherapy in small vessel diseases
Yue Zhanghui,Zhang Qian,Wang Yan,Fang Fang. Application of sclerotherapy in small vessel diseases[J]. International Journal of Dermatology and Venereology, 2017, 43(5). DOI: 10.3760/cma.j.issn.1673-4173.2017.05.004
Authors:Yue Zhanghui  Zhang Qian  Wang Yan  Fang Fang
Abstract:Sclerotherapy,an effective technique for the treatment of vasodilatation,exerts its therapeutic and cosmetic effects by injecting sclerosing agents into blood vessels to make them into fibrous stripes followed by absorption by surrounding tissues.Sclerotherapy is the first choice for the treatment of dilated intradermal venules,including reticular varicosities and telangiectasia,and also has good therapeutic effects on low-flow vascular nalformations.Many factors can affect clinical effects of sclerotherapy,such as types of sclerosing agents,stability of foamed sclerosants and injection methods.With extensive application of sclerosing agents in clinic and improvement of the technology of manufacturing sclerosing foam,the working concentration and dosage of some sclerosing agents have reached a consensus.With development in sclerotherapy and application of newly-emerging technology such as imaging techniques,some progress in sclerotherapy has been made,providing deeper insights into the effectiveness and safety of sclerotherapy,
Keywords:Blood vessels  Telangiectasis  Vascular malformations  Sclerotherapy  Therapeutic uses
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