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冷球蛋白血症性肾炎的临床病理特点
引用本文:龚再良,朱雪婧,袁曙光,杨淡昳,张磊,王畅,李勰家,刘映红,刘虹. 冷球蛋白血症性肾炎的临床病理特点[J]. 国际病理科学与临床杂志, 2017, 37(7). DOI: 10.3978/j.issn.2095-6959.2017.07.009
作者姓名:龚再良  朱雪婧  袁曙光  杨淡昳  张磊  王畅  李勰家  刘映红  刘虹
作者单位:中南大学湘雅二医院肾内科,中南大学肾脏病研究所,长沙 410011
基金项目:国家自然科学基金,中南大学自由探索计划(2012QNZT146).This work was supported by the National Natural Science Foundation,Free Explore Plan of Central South University,China
摘    要:目的:分析冷球蛋白血症性肾炎的临床病理特点,以提高其诊治率.方法:回顾性分析2014年8月至2015年7月中南大学湘雅二医院确诊的冷球蛋白血症性肾炎的3例患者的临床资料.结果:3例冷球蛋白血症性肾炎患者中2例为中年女性,1例为青年男性,所有患者均伴有系统性损伤的表现,3例患者的冷球蛋白的血清冷凝集试验为阳性.2例合并HBV感染,1例合并HCV感染.结论:冷球蛋白血症性肾炎有其独特的肾脏病理特征,肾活检可提高冷球蛋白血症性肾炎的诊断率,提高临床医生对此病的认识,及早进行标准化的治疗.

关 键 词:冷球蛋白血症性肾炎  临床病理特点  诊断

Clinicopathological features of cryoglobulinemic glomerulonephritis
GONG Zailiang,ZHU Xuejing,YUAN Shuguang,YANG Danyi,ZHANG Lei,WANG Chang,LI Xiejia,LIU Yinghong,LIU Hong. Clinicopathological features of cryoglobulinemic glomerulonephritis[J]. Journal of International Pathology and Clinical Medicine, 2017, 37(7). DOI: 10.3978/j.issn.2095-6959.2017.07.009
Authors:GONG Zailiang  ZHU Xuejing  YUAN Shuguang  YANG Danyi  ZHANG Lei  WANG Chang  LI Xiejia  LIU Yinghong  LIU Hong
Abstract:Objective: To summarize the clinical and pathological features of cryoglobulinemic glomerulonephritis. Methods: We reviewed the clinical date of 3 patients with cryoglobulinemia admitted to the Second Xiangya Hospital of Central South University from August 2014 to July 2015.Results: There were two middle-aged women and one young men, and all patients were accompanied by systemic damage, and serum cryoglobulin were positive. Two cases were associated with HBV infection and one with HCV.Conclusion: Cryoglobulin glomerulonephritis has unique pathological features, which could be contributed to the early diagnosis of disease and early treatments.
Keywords:cryoglobulinemic glomerulonephritis  clinicopathological features  diagnosis
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