| 长链非编码RNA在肿瘤发生、发展中的作用研究现状 |
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| 引用本文： | 季青,李琦.长链非编码RNA在肿瘤发生、发展中的作用研究现状[J].中国癌症杂志,2011,21(3). |
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| 作者姓名： | 季青 李琦 |
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| 作者单位： | 上海中医药大学附属普陀医院实验中心,上海中医药大学中西医结合肿瘤介入研究所,上海,200062 |
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| 基金项目： | 上海市教育委员会基金资助项目 |
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| 摘 要： | 长链非编码RNA(long non-coding RNA,IncRNA),有别于其他小分子非编码RNA,是目前非编码RNA研究的热点.随着研究的不断推进,人们发现lncRNA与物种进化、胚胎发育、物质代谢以及肿瘤发生等都有着密切的联系,其功能的深入研究将使目前对细胞的结构网络和调控网络的认识带来革命性的变化,也为未来临床疾病尤其是肿瘤的诊断和治疗提供非常有价值的科学依据.本文对IncRNA在人类肿瘤发生、发展中的研究现状作一综述.
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| 关 键 词： | 长链非编码RNA 肿瘤 研究现状 |
Research status of the long non-coding RNAs in the development of tumor |
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| JI Qing,LI Qi.Research status of the long non-coding RNAs in the development of tumor[J].China Oncology,2011,21(3). |
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| Authors: | JI Qing LI Qi |
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| Institution: | JI Qing,LI Qi(Lab Center,Putuo Hospital,Shanghai University of Traditional Chinese Medicine,Interventional Cancer Institute of Chinese Integrative Medicine,Shanghai 200062,China) |
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| Abstract: | At present,long non-coding RNAs(lncRNAs) are hot spots which are different from other smaller non-coding RNAs.Through researches,lncRNAs have been found to affect species evolution,embryonic development,metabolism and tumorigenesis.Research of IncRNAs will make revolutionary changes in the understanding of the networks of cell structure,regulatory networks,as well as provide scientific evidence for future diagnosis and treatment of clinical diseases,especially in human tumors.In this review,we summarized re... |
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| Keywords: | lncRNA Tumor Research status |
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