中医药治疗小儿乳糖不耐受症腹泻的临床研究

受检对象486例均为1岁半以内腹泻婴幼儿,采用新鲜粪便pH值、醋酸铅法、层析法检测,小儿乳糖不耐受症(LI)诊断标准为:pH<6,醋酸铅法( ),层析法( )。对其中148例LI的患儿分3组治疗观察,Ⅰ组为常规西药治疗,Ⅱ组为常规西药及去乳糖饮食疗法,Ⅲ组为中药治疗,并根据急性(湿热)和慢性、迁延性(脾虚)各给予止泻Ⅰ号、止泻Ⅱ号,急性腹泻观察5天,慢性、迁延性腹泻观察10天。结果486例婴儿腹泻中LI发病率为54.73％,其中慢性、迁延性腹泻发病率为72.73％;对急性腹泻LI,各组疗效差异无显著性(P>0.05);对慢性、迁延性者,则Ⅱ、Ⅲ组疗效优于Ⅰ组(P<0.05);去乳糖饮食疗法对急、慢性、迁延性腹泻LI有较好疗效,慢性、迁延性腹泻LI应用中药治疗能迅速缓解吐泻、腹胀,疗效显著。

Clinical Study on Infantile Lactose Intolerant Diarrhea Treated by TCM

The subjects were 486 cases aged all under 1. 5 -year -old. Their fresh stool were observed closely by pH value, lead acetate (la) method and chromatography. Standards for lactose intolerant (LI) included pH < 6, la 2 ,chromatography . 148 cases were assigned to 3 groups. Group I was treated with regular western drug: group II. regular western drug plus delactose diet; group III, traditional Chinese remedies with Zhixie I, Zhixie II administered to acme (damp - heat), chronic (persisting) types, and observed for 5 and 10 days respectively. Results showed that the incidence of LI in 486 cases infantile diarrhea was 54. 73%, of them, the incidence of chronic type being 72. 73%. For acute diarrhea LI. there was no significant difference among its group (P>0. 05). While for the chronic group, the effects in II, III were superior to I (all P<0. 05). Delactose diet yielded good effect for both types of LI. For chronic persisting LI. traditional Chinese remedies can rapidly ameliorate vomiting, diarrhea and abdominal distention with satisfactory effect.