黄芪建中颗粒的提取工艺优选

目的:优化黄芪建中颗粒的提取工艺.方法:采用正交试验及响应面分析法,以芍药苷提取量和干膏得率为指标,考察中加水量、提取时间及提取次数等因素对黄芪建中颗粒提取工艺的影响.结果:最佳提取工艺条件为加8倍量水提取3次,每次1h,芍药苷转移率达87.4％.结论:优选的提取工艺简单、经济、实用,适合于黄芪建中颗粒有效成分提取.

Optimization of Extraction Technology of Huangqi Jianzhong Granules

Objective: To optimize extraction technology of Huangqi Jianzhong granules. Method: Water extraction technology was optimized by orthogonal design method and response surface method with yield of paeoniflorin and dry extract as indexes.Effects of the amount of water,extraction time and times on extraction technology of Huangqi Jianzhong granules was investigated,and extraction effect of this two methods was compared in order to choose the better one,transfer rate of paeoniflorin of 87.4%. Result: Optimum extraction procedure was:extracted 3 times with 8 folds of water,1 hour each time. Conclusion: This process was simple,economical,practical and suitable for extraction of active ingredients from Huangqi Jianzhong granules.