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Intensive care unit-acquired infection as a side effect of sedation
Authors:Saad Nseir  Demosthenes Makris  Daniel Mathieu  Alain Durocher  Charles-Hugo Marquette
Affiliation:1.Intensive Care Unit, Calmette Hospital, University Hospital of Lille, boulevard du Pr Leclercq, 59037 Lille cedex, France;2.Intensive Care Unit, University Hospital of Larisa, University of Thessaly, Biopolis Street, 41110 Larisa, Greece;3.Respiratory Disease Department, University Hospital of Nice, Hôpital Pasteur, 30 avenue de la voie Romaine, BP 69, 06002 NICE cedex 1, France
Abstract:

Introduction  

Sedative and analgesic medications are routinely used in mechanically ventilated patients. The aim of this review is to discus epidemiologic data that suggest a relationship between infection and sedation, to review available data for the potential causes and pathophysiology of this relationship, and to identify potential preventive measures.
Keywords:
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