| 幽门螺杆菌感染与儿童特发性血小板减少性紫癜 |
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| 引用本文： | 刘巧. 幽门螺杆菌感染与儿童特发性血小板减少性紫癜[J]. 国际儿科学杂志, 2010, 37(3). DOI: 10.3760/cma.j.issn.1673-4408.2010.03.034 |
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| 作者姓名： | 刘巧 |
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| 作者单位： | 重庆医科大学附属儿童医院血液科,400014 |
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| 摘 要： | 特发性血小板减少性紫癜(ITP)是以自身抗体介导的血小板破坏为特征的一组疾病,近年来许多研究显示部分成年人ITP的发生与幽门螺杆菌(Hp)感染密切相关,清除Hp后ITP患者的血小板数量有明显提高.研究认为Hp相关的ITP与抗原交叉反应有关,但其确切机制目前尚不明确;儿童ITP是否需要清除Hp治疗,国内外也存在争议.
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| 关 键 词： | 特发性血小板减少性紫癜 幽门螺杆菌感染 儿童 |
Helicobacter pylori infection and idiopathic thrombocytopenic purpura in children |
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| LIU Qiao. Helicobacter pylori infection and idiopathic thrombocytopenic purpura in children[J]. International Journal of Pediatrics, 2010, 37(3). DOI: 10.3760/cma.j.issn.1673-4408.2010.03.034 |
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| Authors: | LIU Qiao |
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| Abstract: | Idiopathic thrombocytopenic purpura(ITP) is characterized by platelet destruction which is mediated by auto-antibodies. Recent researches show that helicobacter pylori infection is correlated with part of FTP in adult. Eradication of helicobacter pylori infection has brought dramatically platelet elevation. It was reported that cross reaction played a very important part in the helicobacter related FTP, but the exact mechanism is still unknown, whether the FTP in children needs helicobacter pylori eradication is under debate. |
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| Keywords: | Idiopathic thrombocytopenic purpura Helicobacter pylori infection Child |
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