关于宫颈癌放疗优化方法的探讨

目的 评价宫颈癌在全盆腔常规放疗的后程使用立体定向放射治疗(SRT)的临床效果,探讨这种优化治疗宫颈癌的可行性.方法 49例临床分期及病理类型相同的中、晚期宫颈癌患者,经全盆腔放疗后采用SRT进行推量治疗.随访3～12个月,观察患者肿瘤控制总有效率、放疗后无宫内肿瘤进展率及放疗后不良反应的情况.结果 患者放疗后3个月的肿瘤总有效率为81.6%,无宫内肿瘤进展率为100%,直肠反应发生率为18.4%,膀胱反应发生率为12.2%.结论 优化治疗方式对提高宫颈肿瘤的局部控制率和延长患者的生存期有较好的临床应用价值.

An exploration of the treatment method for cervical cancer with optimization

Objective The treatment results of cervical cancer in post stage stereotactic radiotherapy (SRT) after the whole pelvic cavity radiotherapy, was evaluated to explore the feasibility of this optimal method. Methods Forty-nine moderate or advanced cases of cervical cancer with the same clinical stages and pathologic types in our hospital were treated with the whole pelvic cavity radiotherapy and post stage SRT push doses radiotherapy. They were followed up for 3 to 12 months, the total effective rates, the tumor progressions after radiotherapy and no side effects after radiotherapy in patients were observed. Results After radiotherapy for 3 months, the patients' tumor total effective rates were 81.6%, tumor progression rates without intrauterine were 100%, rectum reaction rates were 18.4% and bladder reaction rates were 12.2%.Conclusions This optimization was feasible to the patients of cervical cancer with better tumors' local control and surviving time's prolongation.