| 脑源性神经营养因子与颞叶癫痫 |
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| 引用本文： | 邓晓清,郑金瓯. 脑源性神经营养因子与颞叶癫痫[J]. 医学综述, 2008, 14(11): 1639-1641 |
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| 作者姓名： | 邓晓清 郑金瓯 |
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| 作者单位： | 1. 南宁市第八人民医院神经内科,南宁,530001
2. 广西医科大学第一附属医院神经内科,南宁,530021 |
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| 摘 要： | 脑源性神经营养因子(BDNF)激活其受体酪氨酸受体激酶B,使海马兴奋性增高,从而促使颞叶癫痫产生。简要综述BDNF与颞叶癫痫之间的相互关系及机制。
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| 关 键 词： | 脑源性神经营养因子 TrkB 兴奋性 颞叶癫痫 |
| 文章编号： | 1006-2084(2008)11-1639-03 |
| 修稿时间： | 2007-11-17 |
Brain-derived Neurotrophic Factor and Temporal Lobe Epilepsy |
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| DENG Xiao-qing,ZHENG Jin-ou. Brain-derived Neurotrophic Factor and Temporal Lobe Epilepsy[J]. Medical Recapitulate, 2008, 14(11): 1639-1641 |
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| Authors: | DENG Xiao-qing ZHENG Jin-ou |
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| Affiliation: | DENG Xiao-qing1,ZHENG Jin-ou2.(1.Department of Neurology,Eighth People's Hospital of Nanning,Nanning 530001,China,2.Department of Neurology,First Affiliated Hospital of Guangxi Medical University,Nanning 530021,China) |
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| Abstract: | Brain-derived neurotrophic factor(BDNF)can increase the excitability of hippocampus by activating its receptor tyrosine kinase B and then result in temporal epilepsy.This article reviews the relationship between BDNF and temporal lobe epilepsy. |
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| Keywords: | Brain-derived neurotrophic factor Tyrosine receptor kinaseB Excitability Temporal lobe epilepsy |
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