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Transport and cytotoxicity of paclitaxel, docetaxel, and novel taxanes in human breast cancer cells
Authors:Marie Ehrlichova  Radka Vaclavikova  Iwao Ojima  Antonella Pepe  Larisa V Kuznetsova  Jin Chen  Jaroslav Truksa  Jan Kovar  Ivan Gut
Institution:(1) Cell Growth Control Laboratory, Institute of Molecular Genetics, Academy of Sciences of the Czech Republic, Videnska 1083, 142 00 Prague 4, Czech Republic;(2) Biotransformation Group, National Institute of Public Health, Srobarova 48, 100 42 Prague 10, Czech Republic;(3) Institute of Chemical Biology and Drug Discovery, State University of New York at Stony Brook, Stony Brook, NY 11794-3400, USA
Abstract:
Keywords:Taxanes  Multidrug resistence  Uptake  Efflux  ABC transporters  Verapamil
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