安神方治疗广泛性焦虑障碍临床观察

目的观察安神方治疗广泛性焦虑障碍（GAD）的临床疗效。方法将120例GAD患者随机分为治疗组和对照组,每组60例,分别给予口服安神方和地西泮治疗,疗程均为4周。以汉密尔顿焦虑量表（HAMA）和副反应量表（TESS）评价疗效和不良反应。结果治疗4周后,两组HAMA分值均比治疗前明显降低,差异有统计学意义（P均〈0.01）;但两组间比较差异无统计学意义。治疗组与对照组TESS量表评分比较差异有统计学意义（P〈0.05）。结论安神方治疗GAD安全、有效且不良反应较小,值得进一步研究推广。

Observation of Anshenfang in treating general anxiety disorder

Objectivce To investigate the efficacy of Anshenfang（ASF） for patients with general anxiety disorder （GAD）. Methods 80 patients with GAD were entered a 4-week randomized controlled trial. They were divided into 2 groups. 40 patients of control group were given diazepam and other 40 of treatment group were given ASF. Efficacy and side effects were evaluated with Hamilton Anxiety Scale （HAMA） and treatment emergent symptom scale （TESS）. Results After 4 weeks of treatment the HAMA decrease values in two groups were less than those before the treatment （P 0.01）. There was on significant difference in response rate between the 2 groups. There was significant difference in TESS between the 2 groups. Conclusion ASF is one of the effective therapies with less emergent symptom in treating GAD, which is worth studying and spreading further more.