血栓抽吸装置在经皮冠状动脉介入治疗中对心肌再灌注的影响

目的:评估血栓抽吸装置在急性心肌梗塞(AMI)急诊冠状动脉介入治疗(PCI)患者治疗中的临床应用。方法:86例行急诊PCI治疗的AMI患者被随机分为血栓抽吸组(41例,应用抽吸导管后再行PCI),直接PCI组(45例,直接行PCI),观察无复流发生率、术后ST段下降率及左心室射血分数等。结果:PCI后血栓抽吸组患者的无复流发生率明显低于直接PCI组(4.9%∶11.1%,P0.05),ST段回落率(66.67%、75.61%)、LVEF(54.02±8.93)%∶(49.23±9.12)%]均优于直接PCI组(P均0.05)。结论:急诊冠脉介入治疗急性心肌梗塞患者时,应用血栓抽吸导管可以降低无复流发生率,改善心功能,且安全有效。

Effects of thrombus aspiration catheter on myocardial reperfusion in patients with acute myocardial infarction treated by primary percutaneous coronary intervention

Objective： To evaluate the effects of thrombus aspiration catheter in treatment of acute myocardial infarction （AMI） patients by primary percutaneous coronary intervention （PCI）. Methods： A total of 86 patients with primary AMI who underwent primary PCI were randomized into two groups, experimental group （41 cases, were treated with aspiration catheter）, control group （45 cases, were routinely treated, and no by aspiration catheter）. The regression rate of ST segment, left ventricular ejection fraction （LVEF）, incidence of no reflow and mortality were followed up after PCI during hospitalization. Results： The coronary no reflow rate of experimental group was less than that of control group （4. 9 % vs. 11.1% , P（0. 05）. The regression rate of ST segment and LVEF in experimental group were more than those of control group respectively （66.67%, 75.61%）, LVEF （54.02 ±8.93）% vs. （ 49.23 ± 9.12） %1, P〈0. 05 all]. Conclusion： Transeatheter aspiration of coronary thrombus using thrombus aspiration catheter followed by direct stenting is an effective method to decrease morbidity of no reflow and improve heart function during pereutaneous coronary intervention in AMI patients.