急性脑血管病患者血清甲状腺素和泌乳素变化及其临床意义

目的 观察急性脑血管病(ACVD)患者血清甲状腺素及泌乳素(PRL)含量的变化。方法 通过放射免疫法检测100例ACVD患者血清三碘甲状腺原氨酸(T3)、甲状腺素 (T4)、促甲状腺激素 (TSH)、反T3(RT3)及泌乳素(PRL)的含量 ,并与51例正常人进行对照。结果 ACVD患者血清T3、T4均明显低于对照组(p<0.01) ,血清TSH、RT3、PRL均显著高于对照组(p<0.01)。出血性中风组上述甲状腺激素及泌乳素变化均高于缺血性中风组(p<0.05) ,且各项指标改变与病变大小及部位有关。 结论 血清甲状腺素及泌乳素有助于判断ACVD病情 ,估计预后 ,对治疗有一定的指导意义。

The change and its significance of serum thyroxin and prolactin in patients of acute cerebrovascular disease

Objective To objective the change of serum thyroxin and prolactin in patients of acute cerebrovascular disease(ACVD). Methods Serum triiodothyronine(T3),thyroxin(T4),thyroid-stimulating hormone(TSH),reverse T3and prolactin(PRL)were detected by radio-immunity assay in100patients of ACVD and51normal people and were compared with each other. Results As compared to those of normal people,in ACVD patients,the levels of serumT3and T4were significantly lower(P<0.01),the levels of serumTSH,RT3and PRLwere all significantly higher(P<0.01).The levels of kinds of serumthyroid hormone and PRLin patients of hemorrhagic stroke group were higher than those in patients of ischemia stroke group and the change of above-mentioned makers were related with lesion size and position. Conclusion Serumthyroxin and prolactin were helpful for judging state of ACVD and estimating prognosis and had some instructional therapy significance.