| 重度子痫前期患者胎盘中内源性一氧化碳的检测 |
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| 引用本文： | 王冠,陈萱,杨海婷.重度子痫前期患者胎盘中内源性一氧化碳的检测[J].中国优生与遗传杂志,2008,16(9):76-77. |
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| 作者姓名： | 王冠 陈萱 杨海婷 |
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| 作者单位： | [1]哈尔滨医科大学附属二院妇产科,哈尔滨150086 [2]黑龙江省电力医院,哈尔滨150000 |
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| 摘 要： | 目的检测重度子痫前期患者胎盘内源性一氧化碳（CO）的水平。方法采用改良的双波长分光光度法，建立回归方程，以此测定18例健康晚孕妇女与19例重度子痫前期患者胎盘匀浆中内源性CO的浓度，并进行分析。结果建立的回归方程为：Y=263、3X-0．178，相关系数为0．966。重度子痫前期患者胎盘内源性CO的水平较正常晚孕组下降（P〈0．05）。结论胎盘内源性一氧化碳可能在妊娠期高血压疾病特别在重度子痫前期的发生中，参与了其病理生理过程，发挥着重要的生理作用。
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| 关 键 词： | 重度子痫前期 内源性一氧化碳 胎盘 分光光度法 |
Studies on the level of placenta endogenous carbon monoxide in patients with serious eclampsism |
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| WANG Guan,CHEN Xuan,YANG Hai-ting.Studies on the level of placenta endogenous carbon monoxide in patients with serious eclampsism[J].Chinese Journal of Birth Health & Heredity,2008,16(9):76-77. |
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| Authors: | WANG Guan CHEN Xuan YANG Hai-ting |
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| Institution: | WANG Guan, CHEN Xuan, YANG Hai - ting (1. Department of Gynecology and Obstetrics, the Second Affiliated Hospital of Harbin Medical University, Harbin 150086 2. The Hospital of Electric Power, Heilongjiang Province Harbin 150000) |
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| Abstract: | Objective： To study the role of placenta endogenous carbon monoxide in patients with serious, eclampsism. Methods： Placenta endogenous carbon monoxide （ CO）, in 18 cases of normal late pregnant women and 19 cases of patients with serious eclamp- sism were measured by improved two- wavelength spectrophotometry, to set up regression equation and analysis the correlation. Re- suits： Regression equation is y =263. 3 x -0. 178, correlation coefficient is 0. 966. Compared with normal late pregnant women, pla- centa endogenous CO level in serious eclampsism groups decreased （ P 〈 0.05） . Conclusion ： Placenta endogenous carbon monoxide may play an important physiological functions in pathogenesis of pregnancy induced hypertension, especially in serious eclampsisin. |
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| Keywords: | Serious eclampsism Endogenous carbon monoxide Placenta Spectrophotometry |
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