| 肠道菌群与非酒精性脂肪性肝病研究进展 |
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| 引用本文： | 周达,范建高.肠道菌群与非酒精性脂肪性肝病研究进展[J].传染病信息,2015(4). |
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| 作者姓名： | 周达 范建高 |
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| 作者单位： | 上海交通大学医学院附属新华医院消化内科,200092 |
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| 基金项目： | 国家重点基础研究发展计划(973计划)项目(2012CB 517501)；国家自然基金(81070322、81270491、81470840)；上海市科委课题(0914090350、10411956300)；中国肝炎防治基金(XJS20120501)；上海市卫生局百人计划(XBR 2011007) |
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| 摘 要： | 非酒精性脂肪性肝病(nonalcoholic fatty liver disease,NAFLD)发病率不断升高,对其发生、发展及防治研究变得极为迫切。近年来肠道菌群被认为是机体一个重要的"特殊器官",参与机体代谢及相关疾病的发生、发展,与NAFLD关系密切。本文就肠道菌群与NAFLD的关系研究进行综述。
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| 关 键 词： | 脂肪肝 肠杆菌科 生态失调 内毒素类 乙醇 |
Research progress of the correlation between intestinal microbiota and nonalcoholic fatty liver disease |
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| Abstract: | Currently, the morbidity of nonalcoholic fatty liver disease (NAFLD) is increasing, so it is extremely pivotal to study the development, progression, prevention and treatment of NAFLD. Intestinal microbiota, as an important and special organ of the body, intimately participates in the metabolism of the body, and the development and progression of NAFLD as well. In this article, the correlation between intestinal microbiota and NAFLD is reviewed. |
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| Keywords: | fatty liver Enterobacteriaceae dysbiosis endotoxins ethanol |
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