糖尿病下肢动脉病变的影响因素分析

目的初步分析糖尿病下肢动脉病变（Diabetic lower extremity arterial disease,DLEAD）发病可能的影响因素,为DLEAD的早期发现和临床综合诊治提供参考。方法纳入459例糖尿病患者,均行视诊、问诊、触诊等临床诊察,根据DLEAD判定标准判断患者是否存在DLEAD,并采集其基本信息和相关临床疾病信息。分析DLEAD的可能影响因素。结果有DLEAD组的年龄明显大于无DLEAD组（P〈0.01）,病程亦明显长于无DLEAD组（P〈0.01）。年龄越大,DLEAD的患病率越高。有DLEAD组脂代谢紊乱、高血压病、其他眼病、冠心病、卒中、糖尿病视网膜病变（Diabetic Peripheral Neuropathy,DPN）和糖尿病肾病（Dia-betic Nephropathy,DN）的患病率均明显高于无DLEAD组（P〈0.01）。合并症和并发症越多,DLEAD的患病率越高。冠心病、卒中、高血压病、脂代谢紊乱、DPN和DN对DLEAD危险度估计的OR值分别为4.269、2.717、2.589、2.483、4.067和1.913。结论年龄、糖尿病病程、合并多种伴发病或糖尿病并发症都会影响DLEAD的发病。

Influential factors of diabetic lower extremity arterial disease

Aim To analyze preliminarily the possible influential factors on the onset of diabetic lower extremity arterial disease(DLEAD) in order to provide references for the early discovery and general diagnosis and treatment of DLEAD in clinic.Methods 459 cases with diabetes received clinical examination including inspection,interrogation and palpation.Whether the patient had DLEAD or not was assessed according to the diagnostic criteria of DLEAD.The basic and correlated clinical data were collected.The possible i...