12-year trajectory of health-related quality of life in gastric bypass patients versus comparison groups |
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Authors: | Ronette L. Kolotkin Jaewhan Kim Lance E. Davidson Ross D. Crosby Steven C. Hunt Ted D. Adams |
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Affiliation: | 1. Quality of Life Consulting, Durham, North Carolina;2. Department of Community and Family Medicine, Duke University School of Medicine, Durham, North Carolina;3. Western Norway University of Applied Sciences, Førde, Norway;4. Centre of Health Research, Førde Hospital Trust, Førde, Norway;5. Morbid Obesity Centre, Vestfold Hospital Trust, Tønsberg, Norway;6. Department of Health, Kinesiology and Recreation, College of Health, University of Utah, Salt Lake City, Utah;g. Department of Exercise Sciences, Brigham Young University, Provo, Utah;h. Department of Clinical Research, Neuropsychiatric Research Institute, Fargo, North Dakota;i. Department of Psychiatry and Behavioral Science, University of North Dakota School of Medicine and Health Sciences, Fargo, North Dakota;j. Department of Genetic Medicine, Weill Cornell Medicine, Doha, Qatar;k. Division of Cardiovascular Medicine, Department of Internal Medicine, University of Utah School of Medicine, Salt Lake City, Utah;l. Intermountain LiVe Well Center, Salt Lake City, Utah |
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Abstract: | BackgroundFew prospective studies compare long-term health-related quality of life (HRQOL) outcomes between bariatric surgery patients and individuals with severe obesity who do not undergo bariatric surgery.ObjectivesThis 12-year, prospective study evaluated the trajectory and durability of HRQOL changes in gastric bypass patients (surgery group; n?=?418) and compared these changes to 2 nonsurgical groups. The nonsurgery group 1 (n?=?417) sought but did not have surgery; nonsurgery group 2 (n?=?321) had severe obesity but did not seek surgery.SettingBariatric surgery center.MethodsWeight-related (impact of weight on quality of life-lite [IWQOL-Lite]) and general (short-form health survey-36 [SF-36]) HRQOL questionnaires were administered at baseline and 2, 6, and 12 years postsurgery.ResultsAt 12 years, the surgery group showed greatly improved weight-related HRQOL (IWQOL-Lite) and physical HRQOL (physical component summary of short-form health survey-36) from baseline, and differences between the surgery group and both nonsurgery groups were significant for IWQOL-Lite and physical component summary. IWQOL-Lite and physical component summary scores peaked at 2 years, followed by declines from 2 to 6 and 6 to 12 years. Small improvements in mental/psychosocial aspects of HRQOL (mental component summary of short-form health survey-36) seen in the surgery group at 2 years were not maintained at either 6 or 12 years.ConclusionsGastric bypass patients demonstrated significantly higher weight-related and physical HRQOL at 12 years compared with their very low baseline scores, with the trajectory peaking at 2 years. Despite declining HRQOL between 2 and 12 years, the magnitude of improvement supports the clinical relevance of bariatric surgery for enhancing patients’ quality of life. |
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Keywords: | Gastric bypass surgery Health-related quality of life (HRQOL) Cohort trial Impact of weight on quality of life-lite (IWQOL-Lite) Short-form health survey-36 (SF-36) |
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