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Epidemiological investigation of hypertension and its control on maintenance hemodialysis patients in Anhui province
Authors:Ye Lei  Huang Yangyang  Qian Guangrong  Chen Weidong  Wang Chengfu  Han Jiuhuai  Hu Bin  Liu Zhi  Shui Runzhi  Liu Ligang  Li Xiuyong  Shi Guangcai  Wang Wei  Bai Youwei  Ma Shengyin  Zhang Jianghuai  Han Peng  Wang Huaiqing  Chen Jiande  Hu Bin  Sun Bengui  Ye Liping  Wang Suhang  Wang Jinru  Li Kaipeng  Chen Lei  Hao Li  Wang Deguang.
Affiliation:*Nephrology Department, the Second Affiliated Hospital of Anhui Medical University, Hefei 230601, ChinaCorresponding author: Wang Deguang, Email: wangdeguang@ahmu.edu.cn
Abstract:Objective To understand the prevalence, treatment and influence factors of hypertension in maintenance hemodialysis (MHD) patients in Anhui Province. Methods A total of 2724 adult patients on MHD from January 1st 2014 to March 31st 2014 in 26 hospitals of southern, northern and central Anhui Province were investigated. Their demographic characteristics, primary disease, complications, medications, dialysis and laboratory examination were explored. The prevalence treatment rate and control rate of hypertension were analyzed. Associated factors for controlling hypertension [systolic blood pressure (SBP)<140 mmHg and diastolic blood pressure (DBP)<90 mmHg] were assessed by logistic regression analysis. Results (1) The prevalence of hypertension in the hemodialysis patients was 87.0%. Their treatment rate and control rate were 93.2% and 23.9% respectively. The average of SBP was (145.90±21.18) mmHg, and the DBP on average was (83.60±12.21) mmHg. The most commonly used anti-hypertensive drug is calcium channel blocker (88.2%). Over one third (45.7%) of patients were treated with two kinds of anti-hypertensive drug, 26.2% with 1 kind, 21.7% with 3 kinds, and 6.4% with 4 kinds or more. (2) Compared with non-hypertension patients, patients with hypertension have older age, higher body mass index (BMI), phosphorus, SBP and DBP, as well as lower hemoglobin and Kt/V (all P<0.05). (3) The multivariate logistic regression analysis showed that Ca>2.50 mmol/L (OR=2.084, 95%CI 1.008-4.307, P=0.047) positively correlated with controlling hypertension, while smoke (OR=0.594, 95%CI 0.356-0.911, P=0.046) and BMI 18.5~23.9 kg/m2 (OR=0.516, 95%CI 0.293-0.907, P=0.022) negatively correlated with it. Conclusions High prevalence yet low control rate of hypertension in MHD patients in Anhui Province were observed. Hypocalcemia may be a protective factor for hypertension control, while smoke and BMI may be risk factors for it.
Keywords:Renal dialysis   Hypertension   Antihypertensive agents  
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