原发性卵巢成熟性囊性畸胎瘤合并甲状腺肿类癌一例报告

卵巢成熟性囊性畸胎瘤合并甲状腺肿类癌是一种罕见的卵巢恶性肿瘤，甲状腺肿类癌来源于生殖细胞肿瘤中的内胚窦瘤，发病率极低，仅占卵巢恶性肿瘤的0.1%。甲状腺肿类癌属于低级别神经内分泌肿瘤，恶性度低，预后良好。诊断中应先排除转移性癌，再与卵巢颗粒细胞瘤、支持细胞瘤、卵巢恶性甲状腺肿等相鉴别。治疗上主要以手术为主，但因该病罕见，尚未建立一套标准的治疗方案。近年来，对于原发性卵巢成熟性囊性畸胎瘤合并甲状腺肿类癌在临床特征、病理及免疫组织化学、治疗等方面均有新的进展，报道1例并就该病的研究进展进行探讨，为后续治疗提供参考。

A Case Report of Primary Ovarian Mature Cystic Teratoma Complicated with Thyroid Carcinoid Disease

Ovarian mature cystic teratoma complicated with thyroid carcinoid is a rare ovarian malignant tumor. Thyroid carcinoid is derived from endodermal sinus tumor in germ cell tumor, and its incidence rate is very low, accounting for only about 0.1% of ovarian malignancies thyroid carcinoid is a low grade neuroendocrine tumor with low malignancy and good prognosis. Metastatic cancer should be excluded first in the diagnosis, and then differentiated from ovarian granulosa cell tumor, supporting cell tumor, malignant ovarian goiter and so on. The main treatment is surgery, but because of the disease is rare, the standard of treatment plan has not yet been established. In recent years, there have been new advances in clinical features, pathology, immunohistochemistry, and treatment for primary ovarian mature cystic teratoma complicated with thyroid carcinoid. This article reports a case and discusses the research progress of the disease, providing a reference for follow-up treatment.