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Comparative study on main compounds in Ginkgo biloba L. base on mathematical statistics
Authors:Yiyi Zhao  Ruyi Guo  Haili Yin  Xintong Fu  Yougen Chen  Hongzhu Guo
Abstract:In this paper, an HPLC-DAD-ELSD method was developed to determine main 20 components of Ginkgo bilobaL. leaves from different ages and sources, including six flavonol glycosides, five terpene lactones and nine organic acids. Using statistics method and establishing relevant mathematics models, the measured data has proceeded correlation analysis, principal component analysis, and regression statistics and the results showed generalityand specific characteristics. We defined p-hydroxybenzoicacid, catechinic, KRcG and ginkgolide A as characteristic indexes representing commonnessand specialityof Ginkgo biloba L. leaf. The four characteristic indexes can reflect the quality of Ginkgo biloba L. leaf, and the internal relations between them are significant.The contents of other compounds could define the quantity relation with characteristic markers. It simplified the approach of quality control, and provided a basis for quality control of Ginkgo biloba L.
Keywords:Ginkgo biloba L.  Statistical analysis  Characteristic markers  Holistic quality evaluation  
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