多模式CT在后循环缺血性孤立性眩晕中的应用价值

目的 探讨多模式计算机断层扫描（computed tomography，CT）在后循环缺血性孤立性眩晕中的应用价值。 

Clinical Value of Multimode CT in the Assessment of Isolated Posterior Circulation Ischemia Vertigo

Objective To explore the clinical value of multimode computed tomography (CT) in the
assessment of isolated posterior circulation ischemia vertigo.
Methods The 320-slice whole-brain computed tomography perfusion (CTP), head and neck
computed tomography angiography (CTA) were performed in 30 patients with clinical diagnosed
isolated posterior circulation ischemia vertigo. The intracranial and extracranial arteries of the
posterior circulation and the whole brain perfusions were observed.
Results Vascular lesions were found in 25 patients (83.33%), among which, 70 vessels were
vertebrobasilar stenosis, 9 vessels were vertebral artery circuity, and 4 were vertebral artery hypoplasia.
Abnormal perfusions were found in 22 patients (73.33%), time to peak (TTP) and mean transit time
(MTT) were prolonged in 20 and 17 patients respectively, and cerebral blood flow (CBF) and cerebral
blood volume (CBV) were reduced in 16 and 13 patients respectively. Responsible artery stenosis was
found in all of the patients with abnormal perfusions, and 15 of which were moderate/severe stenosis.
TTP and MTT of the affected side significantly were prolonged compared with the contralateral side
(P <0.05), but no significant difference of CBV nor CBF was detected between the affected side and
the contralateral side. Perfusion abnormalities associated with the degree of responsible artery stenosis.
Positive incidence of CTP abnormalities was higher in patients with moderate/severe vascular stenosisthan in those with mild/none vascular stenosis (P <0.05).
Conclusion Multimode CT is effective to assess the brain vessels and perfusions of patients with
isolated posterior circulation ischemia vertigo.