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脊柱-骨盆矢状面平衡状态与骨质疏松性椎体压缩性骨折经皮球囊扩张椎体后凸成形效果的关系
引用本文:董洲,陶晖,刘艺明,王善松,李春,胡勇. 脊柱-骨盆矢状面平衡状态与骨质疏松性椎体压缩性骨折经皮球囊扩张椎体后凸成形效果的关系[J]. 中国组织工程研究, 2023, 0(29): 4635-4640
作者姓名:董洲  陶晖  刘艺明  王善松  李春  胡勇
作者单位:1.Department of Orthopedic Oncology Surgery, The First Affiliated Hospital of Anhui Medical University, Anhui Province, Hefei230022;2.Department of Spinal Surgery, The First Affiliated Hospital of Anhui Medical University, Anhui Province, Hefei230022;3.Department of Spinal Surgery, Hefei First People's Hospital, Anhui Province, Hefei230010;
基金项目:National Natural Science Foundation of China, NSFC, (82072492)
摘    要:背景:骨质疏松性椎体压缩骨折的高患病率给社会经济和医疗带来较大的负担,并且临床治疗中对于最佳治疗的时间以及方法存在重大争议,经皮球囊扩张椎体后凸成形治疗可减少椎体压缩性骨折的并发症,减轻疼痛,加强结构完整性。目的:探究脊柱-骨盆矢状面平衡状态对骨质疏松性椎体压缩性骨折球囊扩张椎体后凸成形疗效的影响。方法:回顾性分析2018年8月至2020年1月合肥市第一人民医院收治的74例行球囊扩张椎体后凸成形治疗的病历资料,根据术后随访康复效果分为疗效良好组与疗效欠佳组,每组37例。术前及术后随访比较两组患者的目测类比评分、日本骨科协会评分以及影像学资料等。结果与结论:(1)术后疗效欠佳组有3例患者发生骨水泥渗漏,疗效良好组4例患者发生骨水泥渗漏;(2)在术前与术后1个月时,两组患者的日本骨科协会评分与目测类比评分相比无明显差异(P> 0.05),在术后12个月时均明显改善,其中疗效良好组明显优于疗效欠佳组(P <0.05);(3)术前两组患者的伤椎高度丢失率、Cobb角、骶骨倾斜角、骨盆倾斜角、骨盆入射角、腰椎前凸角、矢状面偏移以及胸椎后凸角相比较均无明显差异(P> 0.05);...

关 键 词:椎体压缩性骨折  骨质疏松  球囊扩张椎体后凸成形术  脊柱-骨盆矢状面  临床疗效

Relationship between spine-pelvic sagittal plane balance and effects of percutaneous balkyphoplasty in the treatment of osteoporotic vertebral compression fractures
Dong Z.,Tao H.,Liu Y.M.,Wang S.S.,Li C.,Hu Y.. Relationship between spine-pelvic sagittal plane balance and effects of percutaneous balkyphoplasty in the treatment of osteoporotic vertebral compression fractures[J]. Chinese Journal of Tissue Engineering Research, 2023, 0(29): 4635-4640
Authors:Dong Z.  Tao H.  Liu Y.M.  Wang S.S.  Li C.  Hu Y.
Abstract:BACKGROUND: The high prevalence of osteoporotic vertebral compression fractures leads to a significant socioeconomic and medical burden, and there are controversies about the optimal timing and treatment methods. Percutaneous balloon kyphoplasty can reduce complications, relieve pain, and enhance structural integrity of the vertebral body. OBJECTIVE: To investigate the influence of spinal-pelvic sagittal balance on the therapeutic effects of percutaneous balloon kyphoplasty on osteoporotic vertebral compression fractures. METHODS: The medical records of 74 patients admitted to Hefei First People's Hospital from August 2018 to January 2020 for percutaneous balloon kyphoplasty were retrospectively analyzed, and the included patients were equally divided into the good outcome and poor outcome groups (n=37 per group) according to the postoperative recovery. The visual analog scale scores, Japanese Orthopaedic Association scores, and imaging data of the two groups were compared at baseline and during the postoperative period. RESULTS AND CONCLUSION: (1) Cement leakage occurred in three patients in the poor outcome group and four patients in the good outcome group postoperatively, respectively. (2) Visual analog scores in both groups at 1 month postoperatively were similar to baseline (P > 0.05), while the scores were improved significantly at 12 months postoperatively, with the good outcome group significantly better than the poor outcome group (P < 0.05). (3) There was no significant difference in the loss rate of injured vertebral height, Cobb angle, angle of pelvic incidence, pelvic tilt, sacral slope, angle of lumbar anterior convexity, sagittal deviation and thoracic lordosis angle between the both groups (P > 0.05) at baseline, while the loss rate of injured vertebral height, Cobb angle, and sagittal deviation in both groups were significantly improved at 1 month postoperatively (P < 0.05). The rate of height loss of the injured spine, Cobb angle, sagittal deviation, thoracic lordosis angle, pelvic tilt, sacral slope were significantly increased in the poor outcome group compared with the good outcome group (P < 0.05), while the angle of pelvic incidence and angle of lumbar anterior convexity were significantly decreased in the poor outcome group compared with the good outcome group at 12 months postoperatively (P < 0.05). (4) Pearson correlation analysis revealed that Japanese Orthopaedic Association scores were negatively correlated with sagittal deviation, thoracic lordosis angle, pelvic tilt, sacral slope, angle of pelvic incidence (P < 0.05), while were positively correlated with the angle of lumbar anterior convexity (P < 0.05). In addition, the visual analog scale scores were positively correlated with sagittal deviation, thoracic lordosis angle, sacral slope, and angle of pelvic incidence (P < 0.05), while were negatively correlated with the angle of lumbar anterior convexity and pelvic tilt (P < 0.05). (5) These results suggest that percutaneous balloon kyphoplasty can correct deformity, stabilize fracture, and relieve pain, thereby benefiting most of the patients with osteoporotic vertebral compression fractures. Moreover, spine-pelvic sagittal plane balance can affect the clinical efficacy. © 2023, Publishing House of Chinese Journal of Tissue Engineering Research. All rights reserved.
Keywords:clinical efficacy  osteoporosis  percutaneous balloon kyphoplasty  spine-pelvis sagittal plane  vertebral compression fracture
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