| 正常范围低血钾浓度与糖代谢异常的相关性分析 |
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| 引用本文： | 黄飞,黄韵,杨枝,徐佰慧,陆洁莉,徐敏,毕宇芳,陈宇红.正常范围低血钾浓度与糖代谢异常的相关性分析[J].中国实用内科杂志,2011(9). |
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| 作者姓名： | 黄飞 黄韵 杨枝 徐佰慧 陆洁莉 徐敏 毕宇芳 陈宇红 |
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| 作者单位： | 上海市内分泌代谢病临床医学中心上海交通大学医学院附属瑞金医院内分泌代谢科上海市内分泌代谢病研究所; |
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| 基金项目： | 上海市科委重大项目(09DZ1950200); 上海市自然基金(10ZR1426400) |
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| 摘 要： | 目的研究正常范围血钾浓度偏低与糖代谢异常的相关性。方法 2010年3月至7月选取上海郊区社区40岁以上常住居民2515名。所有参加者均进行问卷调查,身高、体重、腰围、血压等体格检查和75 g无水葡萄糖口服耐量试验(oral glucose tolerance test,OGTT),并检测血钾、血糖、胰岛素和肝肾功能等。结果 (1)正常血钾水平,随着血钾浓度降低,OGTT 2 h血糖、OGTT 2 h胰岛素、收缩压逐渐增高,且差异有统计学意义(P均<0.05)。(2)在正常血钾浓度范围内,与血钾偏高组(5.1～5.5 mmol/L)相比,血钾偏低组(3.5～4.0 mmol/L)中糖代谢异常的患病风险增高,OR(95%CI)为1.61(1.04～2.48);校正相关混杂因素后,低血钾与糖代谢异常的患病风险仍然相关,OR(95%CI)为1.98(1.11～3.52)。结论 40岁以上人群中,正常范围内的血钾偏低与糖代谢异常显著相关。
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| 关 键 词： | 血钾 糖代谢异常 |
Correlation between normal but low potassium and impaired glucose metabolism |
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| HUANG Fei,HUANG Yun,YANG Zhi,XU Bai-hui,LU Jie-li,XU Min,BI Yu-fang,CHEN Yu-hong.Correlation between normal but low potassium and impaired glucose metabolism[J].Chinese Journal of Practical Internal Medicine,2011(9). |
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| Authors: | HUANG Fei HUANG Yun YANG Zhi XU Bai-hui LU Jie-li XU Min BI Yu-fang CHEN Yu-hong |
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| Institution: | HUANG Fei,HUANG Yun,YANG Zhi,XU Bai-hui,LU Jie-li,XU Min,BI Yu-fang,CHEN Yu-hong.Shanghai clinical center for endocrine and metabolic diseases,Department of endocrinology and metabolism,Shanghai Institute of endocrine and metabolic diseases,Ruijin hospital,Shanghai Jiao Tong University School of Medicine,Shanghai 200025,China |
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| Abstract: | Objective To investigate the correlation between normal but low levels of serum potassium and impaired glucose metabolism.Methods A total of 2515 community residents(aged 40 or above) in suburban Shanghai were recruited in this study.All participants received questionnaire survey,physical checkup for body height,weight,waist circumference and blood pressure,and then underwent 75 g oral glucose tolerance test(OGTT).Data were analyzed using ANOVA,chi-square test and multivariate Logistic regression.Results(1)... |
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| Keywords: | serum potassium Impaired glucose metabolism |
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