血流储备分数的临床应用进展

冠状动脉造影一直被认为是诊断冠状动脉狭窄的金标准,它为我们提供了冠状动脉的解剖信息,但是它易受主观因素影响,且不能提供狭窄的血流动力学信息。最好能在造影的同时增加一项简单、快捷的检查,该检查能给临床医生提供狭窄的血流动力学信息,以评价冠脉狭窄引起的功能改变。如今该检查已经被运用在常规临床工作中,即血流储备分数(fractional flow reserve,FFR)。本文将就FFR的基本原理、特点及其临床应用进行综述。

Updates on clinical use of fractional flow reserve

While coronary angiography is widely accepted as the gold standard investigation to diagnose coronary artery disease and has contributed hugely to our understanding of coronary anatomy,it is highly subjective and does not provide any information on hemodynamics at a site of stenosis.Ideally,a quick,easy-to-use examination should be added to coronary angiography,to provide the physician with information on the haemodynamics of a stenosis that may help evaluate functional impairment caused by coronary stenosi...