| 嗜麦芽窄食单胞菌的天然及获得性耐药机制研究进展 |
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| 引用本文： | 胡立芬,叶英,沈为华,李家斌,李旭. 嗜麦芽窄食单胞菌的天然及获得性耐药机制研究进展[J]. 中国抗生素杂志, 2011, 36(9) |
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| 作者姓名： | 胡立芬 叶英 沈为华 李家斌 李旭 |
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| 作者单位： | 安徽医科大学第一附属医院,安徽医科大学细菌耐药研究所,安徽,230022 |
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| 基金项目： | 国家自然科学基金，％％，％％ |
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| 摘 要： | 嗜麦芽窄食单胞菌,为条件致病菌,近年来感染率在不断增加.其不仅对多种抗生素存在天然耐药性,也可同过耐药基因水平转移获得对临床常见抗菌药物的耐药,本文综述了该菌对临床常见药物尤其是磺胺甲基异噁唑/甲氧苄啶的体外药敏情况,并阐述耐药基因对抗菌药物耐药的作用.
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| 关 键 词： | 嗜麦芽窄食单胞菌 磺胺甲基异噁唑/甲氧苄啶 细菌耐药 耐药机制 |
Study of mechanism about intrinsic and acquired resistance in Stenotrophomonas maltophilia strains |
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| Hu Li-fen,Ye Ying,Shen Wei-hua,Li Jia-bin,Li Xu. Study of mechanism about intrinsic and acquired resistance in Stenotrophomonas maltophilia strains[J]. Chinese Journal of Antibiotics, 2011, 36(9) |
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| Authors: | Hu Li-fen Ye Ying Shen Wei-hua Li Jia-bin Li Xu |
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| Affiliation: | Hu Li-fen,Ye Ying,Shen Wei-hua,Li Jia-bin and Li Xu(The First Affiliated Hospital of Anhui Medical University,Institute of Bacterial Resistance in Anhui Medical University,Anhui 230022) |
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| Abstract: | Stenotrophomonas maltophilia as a paradigm of an intrinsically resistant,opportunistic bacterial pathogen is becoming a common cause of infections.The bacterium has been found to contain a number of chromosomally encoded antibiotic resistance determinants.In addition,S.maltophilia can also capture novel resistant genes and acquire resistance to common clinical antibiotics through horizontal gene transfer.In this paper,we reviewed the in vitro activity of antibiotics against clinical S.maltophilia isolates i... |
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| Keywords: | Stenotrophomonas maltophilia Trimethoprim-sulfamethoxazole Bacterial resistance Resistance mechanism |
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