| 葡萄球菌属中红霉素诱导克林霉素耐药的检测 |
| |
| 引用本文： | 关幼华,周金凤,陈梅,区云枝. 葡萄球菌属中红霉素诱导克林霉素耐药的检测[J]. 中国抗生素杂志, 2011, 36(7) |
| |
| 作者姓名： | 关幼华 周金凤 陈梅 区云枝 |
| |
| 作者单位： | 广东省佛山市南海区人民医院检验科,佛山,528200 |
| |
| 摘 要： | 目的 了解我院临床分离的葡萄球菌红霉素对克林霉素诱导耐药的发生率，为临床医生正确选择药物提供依据。方法 采用K-B纸片方法检测葡萄球菌红霉素和克林霉素的耐药性。按照CLSI/NCCLS推荐的D-试验方法检测克林霉素诱导型耐药情况。结果 152株葡萄球菌中有68株(金黄色葡萄球菌31株，凝固酶阴性葡萄球菌37株)呈红霉素耐药、克林霉素敏感，其中31株D-试验阳性(金黄色葡萄球菌14株，凝固酶阴性葡萄球菌17株)，检出率分别为45.2％、45.9％，其他药敏表型未检出D-试验阳性菌株。结论 克林霉素诱导型耐药发生率高，临床微生物实验室对红霉素耐药、克林霉素敏感的葡萄球菌应常规进行D-试验，报道克林霉素诱导型结果，为临床医生正确用药提供依据。
|
| 关 键 词： | 葡萄球菌属 红霉素 克林霉素 诱导型耐药 D-试验 |
Detection for inducible clindamycin resistance in erythromycin-resistance isolates of Staphylococcus |
| |
| Guan You-hua,Zhou Jin-feng,Chen Mei,Ou Yun-zhi. Detection for inducible clindamycin resistance in erythromycin-resistance isolates of Staphylococcus[J]. Chinese Journal of Antibiotics, 2011, 36(7) |
| |
| Authors: | Guan You-hua Zhou Jin-feng Chen Mei Ou Yun-zhi |
| |
| Affiliation: | Guan You-hua,Zhou Jin-feng,Chen Mei and Ou Yun-zhi(Laboratory of the People's Hospital of Nanhai Foshan Guangdong,Foshan 528200) |
| |
| Abstract: | Objective To investigate the probability of induction of clindamycin resistance in isolates of Staphylococcus from clinical laboratory and give the proofs of using antibiotic for clinical physicians.Methods K-B disk diffusion method was used to test erythromycin resistance and clindamycin resistance in isolates of Staphylococcus.D-test recommended by CLSI/NCCLS was used to examine the inducible resistance of erythromycin to clindamycin.Results A total of 68 strains(31 strains of Staphylococcus aureus,37 tra... |
| |
| Keywords: | Staphylococcus Erythromycin Clindamycin Inducible resistance D-test |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
