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宋内志贺菌的耐药状况及耐药机制
引用本文:鲍春梅,曲芬.宋内志贺菌的耐药状况及耐药机制[J].中国抗生素杂志,2011,36(11).
作者姓名:鲍春梅  曲芬
作者单位:解放军302医院,北京,100039
摘    要:志贺菌是引起胃肠道感染主要病原菌之一.老人、儿童和免疫受损的患者中多发.发达国家流行的主要是宋内志贺菌,而发展中国家虽然长期以来流行的为福氏志贺菌,但近年来宋内志贺菌呈明显增加的趋势,并成为优势菌群.本文就近些年全球宋内志贺菌的分布流行、耐药情况、耐药机制以及检测方法的进行综述.

关 键 词:宋内志贺菌  耐药性  ESBLs  AmpC  β-内酰胺酶  PFGE

Drug-resistance in Shigella sonnei: Epidemiology and mechanisms
Bao Chun-mei,Qu Fen.Drug-resistance in Shigella sonnei: Epidemiology and mechanisms[J].Chinese Journal of Antibiotics,2011,36(11).
Authors:Bao Chun-mei  Qu Fen
Institution:Bao Chun-mei and Qu Fen(The Center of Clinical Laboratory of 302 Hospital,PLA,Beijing 100039)
Abstract:Shigella is one of the common pathogenic bacteria responsible for gastrointestinal infection.The vulnerable population are infants,elders and the immunocompromised.Shigella sonnei is most prevalent in developed countries and is becoming more prevalent in developing countries that have been dominated by Shigella flexneri.In this review,the distribution of Shigella sonnei,the situation of drug resistance,the mechanism of drug resistance and detection of Shigella sonnei were reviewed.
Keywords:
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