胶原蛋白海绵促进牙槽窝早期骨愈合的实验研究

目的:研究胶原蛋白海绵填人拔牙创后胶原蛋白海绵对牙槽窝早期骨愈合的影响.方法:健康成年新西兰大白兔20只,建立兔拔牙模型,左侧拔牙创内植入胶原蛋白海绵为实验侧,右侧拔牙创为空白对照侧.拔牙术后1周、2周、4周、8周、12周处死动物取材,通过骨密度检测和组织学检查评价拔牙创牙槽窝愈合情况.应用SPSS12.0软件包对组间...

An experimental study on collagen sponge promoting bone formation in teeth socket

PURPOSE： To study the effect of collagen sponge implantation in tooth socket on bone healing.METHODS：Twenty adult New Zealand white rabbits were used in this study.Animal models with tooth extraction were established.In the experimental group,the collagen sponge were embedded in the sockets of left side.In the control group,nothing was embedded in the sockets of right side.The rabbits were sacrificed and the specimens were obtained 1,2,4,8 and 12 weeks after surgery for bone density examination and histological observation,in order to evaluate bone healing of tooth socket.Statistical analysis were conducted using SPSS12.0 software package.RESULTS： 1 week,2 weeks,4 weeks and 8 weeks after surgery,the bone density of the experimental group was significantly higher than that of the control group.12 weeks after surgery,no significant difference was observed between the two groups.CONCLUSIONS： Collagen sponge can promote bone healing of tooth socket after tooth extraction.