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氯氮平与舒必利对慢性幻听的疗效观察
引用本文:罗维肖,梁芝国.氯氮平与舒必利对慢性幻听的疗效观察[J].临床精神医学杂志,1999,9(2):70-71.
作者姓名:罗维肖  梁芝国
作者单位:广西贵港解放军第191医院
摘    要:目的:探讨氯氮平、舒必利及两药联用对慢性幻听的疗效。方法:将42例具有慢性幻听的男性病人随机分为三组,分别予氯氮平、舒必利及两药联用,于治疗2、4、8周作简明精神病是一表(BPRS)中幻觉项单项评分评定疗效。结果:治疗结束时联用组显效率为71.4%,氯氮平组和舒必利组分别为21.4%、14.3%。结论:提示氯氮平与舒必利联用能提高对慢性幻听的疗效。

关 键 词:幻听  氯氮平  舒必利  精神分裂症  联合用药  疗效

Combined clozapine and sulpiride in the treatment of chronic resistant auditory hallucination
Luo Weixiao,Liang Zhigwo,Wang Jian et al.Combined clozapine and sulpiride in the treatment of chronic resistant auditory hallucination[J].Journal of Clinical Psychological Medicine,1999,9(2):70-71.
Authors:Luo Weixiao  Liang Zhigwo  Wang Jian
Institution:Luo Weixiao,Liang Zhigwo,Wang Jian et al.The 191 Hospital of PAL,Guigang 537105
Abstract:Objective:To evaluate the efficacy of combined clozapine and sulpiride in the treatment of chronic resistand auditory hallucination. Method:42 male subjects with chronic resistant auditory hallucination were randomly divided into three groups each receiving clozapine,sulpiride and combined treatment respectively for 8 weeks.The clinical response was monitored with BPRS at 2,4 and 8 weeks after starting of treatment. Results:Combined treatment was significantly more effective than either clozapine or sulpiride alone (subjects improved:71 4% vs 21 4%vs 14 3%) in the amelioration of auditory hallucination. Conclusion:A combination of clozapine and sulpiride should be considered in the treatment of chronic resistant hallucination.
Keywords:Auditory hallucination    Clozapine    Sulpiride    Combined treatment
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