脑卒中后汉语语法缺失与脑损害区域的关系

目的　探讨脑卒中后汉语语法缺失与脑损害区域的关系。方法　用汉语语法量表对 60例患者 ( 3 0例左半球卒中患者 ,3 0例右半球卒中患者 )和 3 0例正常对照者进行测试 ,利用统计学结果分析汉语语法缺失与CT所示脑损害区域的关系及意义。应用计算机图像处理技术对 2 0例汉语语法缺失患者的颅脑CT图像进行标准化处理 ,观察病变的集中趋势。结果　①左半球卒中组患者的词类、语序、语用、句图匹配和语言符号操作评分与右半球卒中组、正常对照组间差异均有显著性意义 (P <0 .0 1) ,右半球卒中组与正常对照组的评分仅在句 图匹配项差异存在显著性意义 (P <0 .0 1) ,其它项目差异无显著性意义 (P >0 .0 5 )。②CT图像标准化处理后 ,病变部位主要集中在左额叶和左颞叶。结论　左额 -颞叶神经网络系统损伤与汉语语法缺失密切相关 ,右额 -颞叶神经网络系统参与句法辅助加工 ,完整的汉语语法认知需要大脑两半球的协同活动

The relationship between Chinese agrammatism and cerebral lesion sites in stroke patients

Objective To explore the relationship between Chinese agrammatism and cerebral lesion sites in patients with stroke. Methods Sixty patients (30 with left hemisphere stroke and 30 right hemisphere stroke) and 30 normal control subjects were evaluated by the Chinese Agrammatism Battery (CAB ). The computerized image processing technology (CIPT) were used to standardize the skull CT images of 20 patients to investigate the relationship between the Chinese agrammatism and cerebral lesion sites. Results The scores of lexis, sequence of sentence, grammar, match between sentences and graphs in patients with left hemisphere stroke were significantly lower than those with the right hemisphere stroke and the controls( P <0.01), while there was no difference between the controls and those with right hemisphere stroke( P >0.05) except for the scores of match between sentences and graphs( P <0.01). The skull CT images standardized by CIPT showed that the injury locatedin the left frontal and temporal lobes in patients with Chinese agrammatism. Conclusion The injuries of left frontal temporal neural network might be closely related to Chinese agrammatism; the right hemisphere might be involved in auxiliary processing of syntax.The coordination of bilateral hemispheres is indispensable for the integral cognition of Chinese grammar.