婴儿先天性梅毒中枢神经系统的CT表现

目的 探讨先天性梅毒婴儿的中枢神经系统CT特征。方法 回顾性分析经临床确诊的11例先天性梅毒婴儿的中枢神经系统CT资料。结果 10例新生儿患者在CT上均表现为脑白质的弥漫性密度减低，其中3例合并有蛛网膜下腔出血，1例合并有脑内出血。1例2个月大的患儿表现为两侧额、颞叶脑沟增宽及大脑镰前部蛛网膜下腔增宽，5例经治疗后45d至6个月，CT复查表现为两侧脑沟、脑池、脑裂的增宽，其中3例伴有侧脑室和第3脑室的扩大。结论 先天性梅毒中枢神经系统的CT表现在新生儿类似重度缺氧缺血性脑病，随访复查可呈现外部性脑积水或脑发育不良的表现。

CT findings of central nervous system in congenital syphilis infant

Objective To investigate the CT features of the central nervous system in congenital syphilis infant. Methods CT findings of central nervous system in 11 infants with clinically proved congenital syphilis were analyzed retrospectively. Results CT findings in 10 syphilis neonates were diffuse hypodense lesions in the white matter, with subarachnoid and intra-encephalic hemorrhage in 3 and 1 cases, respectively. One 2-month-old syphilis infant case and 5 cases of follow-up after 45 days to 6 months of treatment demonstrated bilateral widened sulci and cistern with enlarged ventricles in 3 of them. Conclusion CT findings of the central nervous system in congenital syphilis infant are similar to those of hypoxic-ischemic encephalopathy in neonates, and extra-encephalic hydrocephalus or brain hypogenesis ensues later on.