| Graves病患者泪膜功能研究 |
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| 引用本文： | 谢怀林,林育华,王善洁,蒋艳华,曾少杰,李慧娟.Graves病患者泪膜功能研究[J].中国医师进修杂志,2008,31(15):10-12. |
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| 作者姓名： | 谢怀林 林育华 王善洁 蒋艳华 曾少杰 李慧娟 |
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| 作者单位： | 1. 广西壮族自治区南溪山医院眼科,桂林,541002
2. 广西壮族自治区南溪山医院内分泌科,桂林,541002 |
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| 摘 要： | 目的 探讨Graves病患者的泪膜功能.方法 前瞻性研究78例Graves病患者(病例组),对照组为40例健康体检者.分别进行泪膜破裂时间测定(TBUT)、基础泪液分泌试验(SIT)、角膜荧光素染色和眼部干涩、不适症状询问.结果病例组TBUT和SIT与对照组比较,差异均有统计学意义(P＜0.05). TBUT＜10s和自觉有眼干涩症状以及角膜荧光素染色阳性的比率,病例组与对照组比较,差异均有统计学意义.结论 Graves病患者发生泪膜功能异常的比率高于健康体检者,是发生干眼症的易患人群.
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| 关 键 词： | 格雷夫斯病 干眼病 泪膜功能 |
The study of tear film function in Graves disease |
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| XIE Huai-lin,LIN Yu-hua,WANG Shan-jie,JIANG Yan-hua,ZENG Shao-jie,LI Hui-juan.The study of tear film function in Graves disease[J].Chinese Journal of Postgraduates of Medicine,2008,31(15):10-12. |
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| Authors: | XIE Huai-lin LIN Yu-hua WANG Shan-jie JIANG Yan-hua ZENG Shao-jie LI Hui-juan |
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| Abstract: | Objective To investigate the tear fdm function with Graves disease.Methods Seven-ty-eight patients with Graves disease were studied respectiveIy,40 cases healthy person as contr01.Tear film function Was evaluated by tear break-up time(TBUT),Schirmer I test(SIT),corneal fluorescein staining,dry eye and unwell symptoms.Results The difference of TBUT and SIT resultsbetweenpatients and con-trois were significant(P＜0.05).The rate ofTBUT,corneal fluorescein staining and symptom ofdry eye in patients were significantly higher than those in controls.Conclusions Graves disease patients have higher rate of abnormal tear film function in comparison with controls.Graves disease are correlated with xerophthalmia. |
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| Keywords: | Graves disease Xerophthalmia Tear film function |
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