| 玫瑰花糖膏对大鼠胃肠激素的影响 |
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| 引用本文： | 热比姑丽·伊斯拉木,尤力都孜·买买提,夏木西努尔·肖盖提,艾合买提·买买提,凯赛尔·阿不都克热木. 玫瑰花糖膏对大鼠胃肠激素的影响[J]. 中国基层医药, 2011, 18(24): 3313-3314. DOI: 10.3760/cma.j.issn.1008-6706.2011.24.001 |
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| 作者姓名： | 热比姑丽·伊斯拉木 尤力都孜·买买提 夏木西努尔·肖盖提 艾合买提·买买提 凯赛尔·阿不都克热木 |
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| 作者单位： | 1. 830049 新疆维吾尔自治区乌鲁木齐,新疆维吾尔自治区维吾尔医药研究所;830049 新疆维吾尔自治区乌鲁木齐,新疆维吾尔自治区维吾尔医方剂学实验室
2. 新疆维吾尔自治区维吾尔医医院科研科 |
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| 基金项目： | 基金项目：国家十一五科技支撑计划项目（2007BA148806） |
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| 摘 要： | 目的 观察玫瑰花糖膏对大鼠胃肠激素水平的影响.方法 选用Wistar大鼠50只,随机分为空白对照组（0.5％羧甲基纤维素钠）、多潘立酮组（0.0027 g/kg）、玫瑰花糖膏组（4 g/kg、6 g/ks、8 g/kg）,连续灌胃给药20d,用酶联免疫分析测定大鼠血清胃动素（MTL）、血管活性肠肽（VIP）、胃泌素（GAS）水平.结果 与空白对照组比较,玫瑰花糖膏（4 g/kg、6 g/ks）能升高血清VIP水平（P＜0.05～P＜0.01）,对MTL、GAS水平的影响无统计学意义（P＞0.05）.与空白对照组比较,多潘立酮组、玫瑰花糖膏组（8g/ks）能升高血清MTL、GAS水平（P＜0.05）,对VIP水平的影响无统计学意义（P＞0.05）.结论 玫瑰花糖膏对胃肠激素有一定的调节作用,其作用与剂量有关.
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| 关 键 词： | 玫瑰花糖膏 胃肠道激素 酶联免疫法 |
Effect of Qizil Guliqent on gastrointestinal hormone in rats |
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| RABIGUL Islam,YULTUZ Mamat,XAMXINUR Xawkat,AHMAT Mamat,KAYSAR Abdukerim. Effect of Qizil Guliqent on gastrointestinal hormone in rats[J]. Chinese Journal of Primary Medicine and Pharmacy, 2011, 18(24): 3313-3314. DOI: 10.3760/cma.j.issn.1008-6706.2011.24.001 |
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| Authors: | RABIGUL Islam YULTUZ Mamat XAMXINUR Xawkat AHMAT Mamat KAYSAR Abdukerim |
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| Affiliation: | RABIGUL Islam, YULTUZ Mamat , XAMXINUR Xawkat,AHMAT Mamat,KAYSAR Abdukerim. The Inistitute of Xinjiang Traditional Uygur Medicine of Xinfiang Uygur Autonomous Region, Urumqi ,Xinfiang 830049, China |
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| Abstract: | Objective To investigate the effect of Qizil guliqent on gastrointestinal hormone in normal rats.Methods The rats in experimental groups were administered with Qizil guliqent(4g/kg,6g/kg,8g/kg ),madinglin (0.0027g/kg),and the rats in normal control group were given 0.5％ CMC-Na for twenty days.The method ELISA was used to detect the content of gastric motility(MTL),vasoactive intestinal peptide(VIP) and Gastrin(GAS) in serum of normal rats.Results In comparison with normal control group,VIP increased in Qizil guliqent group(4g/kg,6g/kg) (P ＜0.05 ～P ＜ 0.01 );but MTL,GAS were not significantly changed in this group( P ＞ 0.05 ).MTL,GAS were increased in Qizil guliqent group ( 8g/kg ) and madinglin group (0.0027g/kg) ( P ＜ 0.05 ) ; but VIP was not significantiy changed in this group(P ＞ 0.05 ).Conclusion Qizil guliqent could regulate gastrointestinal hormones in rats,and dose related. |
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| Keywords: | Qizil guliqent Gastrointestinal hormone ELISA |
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