南蛇藤活性成分及药理作用研究概况

南蛇藤属卫矛科南蛇藤属植物,全国均有分布,但以长江以南地区多见。其主要的化学成分包括萜类化合物、脂类化合物、苷类化合物及黄酮类化合物,其药理作用广泛;主要的药理作用包括抗肿瘤、抗炎、免疫调节、抗菌、抗氧化、抗纤维化及抗生育作用等。笔者主要综述了近几年南蛇藤活性成分的分离,以及在上述药理作用方面的研究进展,以期为南蛇藤的研究与开发提供借鉴与思考。

Progress on active compositions and pharmacological effects of Celastrus orbiculatus

Celastrus orbiculatus Thunb. (Celastraceae) was widely distributed in China and more in the south area of the Yangtze River. Research showed the main chemical components including terpenoids, lipids, glycosides and flavonoids. Its pharmacological effects were extensive, which were including antitumor, anti-inflammatory, immunomodulatory, anti-fibrosis and anti-fertility etc. The separation of active compositions and advances in the pharmacological effects were reviewed in recent years, which would be helpful in providing reference and thinking for the research and development of Celastrus orbiculatus.