MUSCLE BIOPSY FOR DIAGNOSIS OF MALIGNANT HYPERTHERMIA SUSCEPTIBILITY IN TWO PATIENTS WITH SEVERE EXERCISE-INDUCED MYOLYSIS |
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| Authors: | HACKL, W. WINKLER, M. MAURITZ, W. SPORN, P. STEINBEREITHNER, K. |
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| Affiliation: | MH-Investigation Unit of the Ludwig Boltzmann Institute of Experimental Anaesthesiology and Research in Intensive Care Medicine Spitalgasse 23, A-1090 Vienna, Austria
Department of Anaesthesiology, Krankenanstalt Rudolfstiftung Juchgasse 25, A-1030 Vienna, Austria |
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| Abstract: | Muscle biopsy and in vitro contracture tests for diagnosis ofsusceptibility to malignant hyperthermia (MH) were performedin two patients who had developed fever and severe myolysisduring exercise. MH susceptibility was confirmed in one patientbut in the other, exercise-induced heat stroke proved to bethe correct diagnosis. Clinical presentation and epidemiologyof exercise-induced MH and its relation to the heat stroke syndromeare discussed. |
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