常州市成人血脂异常的流行特征分析

目的探讨常州地区当前一般人群血脂异常的流行特点。方法利用2012年1 259名健康检查者资料,分析并比较不同性别、不同年龄人群血清甘油三酯（TG）、总胆固醇（TC）、高密度脂蛋白胆固醇（HDL-C）、低密度脂蛋白胆固醇（LDL-C）的异常率以及TG与TC、LDL-C、HDL-C的关系。结果①男性TG、TC、LDL-C、HDL-C异常率均高于女性,按年龄分层,男女TC、LDL-C异常率均随年龄增加呈上升趋势,但男性TG异常率与年龄不呈正比。无论男性还是女性,不同年龄段HDL-C异常率未见统计学差别。②男性血脂异常者中有49.9%为混合型,女性则有52.2%为混合型。③logistic回归分析表明,校正性别、年龄后,TG异常与TC异常呈正相关（OR 95%CI=1.563~3.409）,与HDL-C异常呈负相关（OR 95%CI=0.246~0.974）。结论常州地区成年人血脂异常率较高,且混合型血脂异常占较高比例,今后应积极开展预防血脂异常的健康教育。

Analysis on epidemiological characteristics of dyslipidemia among adults in Changzhou City

Objective] To study epidemiological characteristics of dyslipidemia among general population in Changzhou City. Methods]Based on the health examination data of 1 259 healthy subjects, the abnormal rates of triglyceride （TG）, total cholesterol （TC）, high low-density lipoprotein cholesterol （LDL-C） and low high-density hpoprotein cholesterol （HDL-C）, as well as the relationship between TG and TC, LDL-C, HDL-C in different sex and age groups were analyzed and compared. Results]（1） The abnormal rates of TG, TC, LDL-C and HDL-C in males were higher than those in females. According to the age stratification, the abnormal rates of TC and LDL-C in males and females increased with increasing age, but the abnormal rate of TG in males was not positively relat- ed to the age. Whether in males or females, there were no statistically significant differences in abnormal rate of HDL-C among different age groups. （2）49.9% of male patients with dyslipidemia and 52.2% of female patients were identified as mixed type. （3）The logistic regression analysis showed that： after adjusting the sex and age, the abnormal TG level had a positive correlation with abnormal TC level （OR 95% CI = 1. 563-3. 409）, while it negatively related to abnormal HDL-C level { OR 95% CI = 0. 246-0. 974）. Conclusion] The prevalence of dyslipidemia among adults in Changzhou City is high, and ,nixed dyslipidemia accounts for greater proportion. In the future, it is necessary to actively carry out the health education to prevent the dyslipidemia.