规模化社区乙型病毒性肝炎及相关疾病现患率调查

目的了解天津市乙型病毒性肝炎（hepatitis B，HB）及相关肝硬化（liver cirrhosis，LC）、肝癌（hepatocellular carcinoma，HCC）的现患率，探讨疾病的调查研究新方法。方法采取多阶段整群抽样方法，将天津市16个区县（滨海新区含塘沽、汉沽及大港片区）按行政区分层，从中抽取12个街／乡为社区监测点，监测点中的全部居民为研究对象。采用网络报告、医院就诊登记和社区咨询服务3种途径搜索HB、LC和HCC。结果共搜索HB及相关疾病2348例，经调查确认1700例，其中HB、LC和HCC分别为1267例、318例和115例。2012年天津市HB、LC、HCC患病率分别为231．30／10万、58．05／10万、20．99／10万，HB及相关疾病总患病率为310．34／10万。HB、LC、HCC患病年龄中位数分别为48、61和60岁。结论通过3种途径搜索被人们误解的HB及相关疾病是当前科学、有效的方法，调查出的社区HB、LC和HCC现患率较报告发病率更有实际意义。

Survey on prevalence rate of hepatitis B and related diseases in large scale community

Objective] To investigate the prevalence rate of hepatitis B （HB}, liver cirrhosis （LC） and hepatocellular carcinoma （HCC） in Tianjin, explore a new investigation method. Methods] Multistage stratified cluster random samplings were adopted in this study. Based on 16 districts/counties in Tianjin （the Binhai New Area includes the district of Tanggu, Hangu and Dagang）, 12 communities were chosen to be the surveillance sites, and all residents in these communities were the samples. The cases of HB, LC and HCC were searched from the diseases reporting network system, hospital information system （ HIS } and community consultation. Results ] A total of 2 348 HB and related diseases cases were searched out, and 1 700 cases were confirmed by inves- tigation, including 1 267 HB cases, 318 LC cases and 115 HCC cases. The prevalence rate of HB, LC and HCC in Tianjin was re- spectively 231.30/lakh, 58.05/lakh and 20.99/lakh, while the total prevalence rate of HB and related diseases was 310.34/lakh. The median age of patients with HB, LC and HCC was 48 years old, 61years old and 60 years old, respectively. Conclusion ] The method for searching cases in this research is a scientific and effective idea onmethodology of how to make the surveys of misunder- standing illnesses, and the result of the research is more practical and applicable than the reported incidence rate.