青翘石油醚提取物的抑菌活性研究

目的:研究青翘石油醚提取物的抑菌活性。方法:青翘石油醚提取物以石油醚-乙酸乙酯为流动相通过硅胶柱层析得到不同极性组分。以金色葡萄球菌、大肠杆菌和白色念球菌为代表菌种,用K-B纸片扩散法对不同极性组分的抑菌活性进行了初步研究。结果:青翘石油醚提取物各极性组分对供试菌均有一定的抑制活性,但抑菌活性与各组分浓度不成简单的正比关系。结论:青翘不同极性组分对金色葡萄球菌、大肠杆菌和白色念球菌均有抑制作用。

Study on Antimicrobial Activities of Petroleum Ether Extract from Green Forsythia suspensa

Objective: To study the antimicrobial activities of petroleum ether extract from Green Forsythia suspensa. Method :The petroleum ether extract was subjected to column chromatography on silica gel using petroleum ether with increasing volume of ethyl acetate as eluent to give different fractions. The antimicrobial activities of different fractions on Staphy lococus aureua, Escherichia coli and Candida albicans were studied by K-B paper dispersion. Result: The petroleum ether extract from green F. suspense showed antimicrobial activity against tested mold. But the antimicrobial activities of all the fractions were not relevant to the concentration of extract. Conclusion: The antimicrobial activities of different fractions on S. lococus aureua, E. coli and C. albicans were significant.