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Ethylene vinylacetate copolymer particles dissolved in polyvinyl alcohol (2,000-mer) solution as an embolic material for vascular anomalies
Authors:A. Kinoshita  K. Yamada  M. Ito  M. Yamazaki  M. Taneda  T. Hayakawa
Affiliation:(1) Department of Neurosurgery, Teramoto Memorial Hospital, Kawachinagano, Japan;(2) Department of Neurosurgery, Osaka University Medical School, 2-2 Yamadaoka, 565 Suita, Japan
Abstract:We have prepared a new material for embolisation: ethylene vinylacetate copolymer dissolved in polyvinyl alcohol. When in contact with blood, polyvinyl alcohol rapidly becomes a soft gel, which is accompanied by wedging of the ethylene vinylacetate copolymer. We analysed the histopathology of intra-arterial microemboli in rats, after intracarotid injection of this material. We confirmed that it was applicable to embolisation for neurosurgical treatment.
Keywords:Ethylene vinylacetate copolymer  Polyvinyl alcohol  Embolisation  Arteriovenous malformations
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