“人工颈椎复合关节系统”的优化设计及生物力学评价

目的:优化人工颈椎复合关节系统(artificialcervical joint complexACJC)并进行生物力学评价.方法:在前期设计的基础上,以及通过测量工作得到的关于正常人体颈椎解剖和运动学参数,优化ACJC.新鲜的人体颈椎标本14具,随机取出7具作为正常颈椎组,在MTS858Mini Bionix II生物材料实验系统进行稳定性实验并测定各节段椎间活动度.随后将标本随机分为钢板固定组和假体植入组,每组7例,对每组标本分别进行实验前处理:钢板固定组依次行前路C5椎体次全切、植骨融合内固定术;假体植入组依次行C5椎体次全切、假体植入术.试验同正常颈椎组.结果:稳定性实验显示假体植入组与正常颈椎组相比,下颈椎在三维六自由度的ROM均无显著差异.而钢板固定组在前屈、后伸、左右侧弯中的活动范围(ROM)均小于显著其余两组.手术节段活动度测定显示,钢板固定组的各向ROM均显著小于其余两组,而假体植入组仅在后伸运动中ROM显著大于正常颈椎组,其余活动中均与正常颈椎组无显著差异.临近椎间活动度测定显示,三组间下位椎间隙活动度无显著差异;对于上位椎间隙,假体植入组与正常颈椎组无显著差异.钢板固定组前屈、后伸活动度...

Optimal design and biomechanical assessment of artificial cervical joint complex

AIM:To optimze the design and perform biomechanical assessment of artificial cervical joint complex.METHODS:Based on the geometric and movement parameters of human' cervical spine,we optimized and manufactured artificial cervical joint complex(ACJC)with titanium alloy.Drawing out 7 samples of 14 fresh cervical spines as intact group randomly,carried on the experiments on stability under the biomaterial experimental system of MTS 858 Mini Bionix II.Divided 14 cervical spines into 2 groups including plate-scr...