ApoA—IApoB及比值与冠状动脉粥样硬化斑块易损研究

目的探讨与动脉粥样硬化的易损性相关的指标以及同ApoA—I、ApoB及其比值的关系。方法选取本院收治的72例冠状动脉粥样硬化患者进行超声检查，按照检查结果分为稳定斑块及易损性斑块两组进行。观察两组病人的各项临床指标。结果经过对两组观察比较后发现，易损性斑块组较稳定性斑块组在Non．HDLC、ApoB、ApoB／ApoA—I等指标上有上升趋势，相反ApoA—I则有下降趋势。另外发现ApoB／ApoA—I比值独立对易损性动脉粥样硬化发生的危险性具有一定的影响。结论ApoB／ApoA—I可以作为发生冠状动脉易损性动脉粥样斑块的一项预测指标。

Relationship between ApoB/ApoA -I ratio and carotid atherosclerotic plaque

Objective To study the relationship between the ApoB/ApoA - I ratio and carotid atherosclerotic plaque. Methods Screening out 72 patients undergoing coronary angiography. Concentrations of ApoB, ApoA - I, ApoB/ ApoA - I,TC,TG, LDL, HDL and the relationships with SYNTAX score were analyzed. Results There was linear re- gression relationship between ApoB/ApoA - I ratio and the SYNTAX score. Conclusion The ApoB/ApoA - I ratio is a better predictor of the coronary lesion level than other lipid index.